With their hopes of a shock appearance in the Champions League knockout rounds hanging by the thinnest of threads, Club Brugge play host to RB Leipzig in Wednesday's Group A clash.
Meanwhile, Jesse Marsch's men are already eliminated from Europe's premier competition and can only salvage a spot in the Europa League at this late stage.
Match preview
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Brugge shocked many by taking four points from their first two clashes with Leipzig and Paris Saint-Germain, but a pair of heavy defeats to last season's beaten finalists Manchester City has brought the Belgian champions crashing back down to earth.
After shipping five to the Citizens on their own turf, Brugge fell to a 4-1 defeat at the hands of Pep Guardiola's men at the Etihad Stadium, with Raheem Sterling, Riyad Mahrez, Phil Foden and Gabriel Jesus all on target for the home side.
Philippe Clement's men are not entirely out of the running for a top-two finish as they sit third in Group A, and at least one of Man City or PSG will drop points in their clash this week, so a positive result on home soil will keep their faint hopes of a knockout berth alive.
However, Brugge do not exactly have the wind in their sails heading into this contest as they suffered a 2-1 defeat to KV Mechelen in the league at the weekend, meaning that they are without a win in three games across all competitions since the start of the month.
On a more positive note, Brugge have kept up their hot streak of scoring in every game they have played in this season and have not failed to find the back of the net at home since March, which ought to spell trouble for a leaky Leipzig defence.
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Meanwhile, Leipzig's doomed Champions League campaign cannot end soon enough, as the Bundesliga outfit hold the unfortunate title of being the Group A whipping boys, but they did at least manage to take a point off Paris Saint-Germain last time out.
Georginio Wijnaldum's brace came after ex-PSG prospect Christopher Nkunku had opened the scoring for Leipzig, and in the second minute of second-half injury time, Dominik Szoboszlai restored parity from the spot to claim Leipzig's first point of the group stage.
Marsch's side had already seen their hopes of a last-16 appearance dashed by three opening defeats in succession - with life after Julian Nagelsmann not exactly rosy - and their five-game unbeaten run in all tournaments came to end at the weekend in a 2-0 defeat to Hoffenheim.
Leipzig had started to show a bit of fight with that hot streak but cannot afford to dwell on that dampening defeat for too long, as the visitors must seek to end a miserable run of only two wins from 10 on the road this term, both of which came in the DFB-Pokal.
Goals from Hans Vanaken and Mats Rits saw Brugge prevail 2-1 against Leipzig during their meeting in September, and one would not put it past the Belgian side to repeat the same trick here against a depleted visiting contingent.
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Team News
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Brugge midfielder Eder Balanta returns from a continental suspension for the visit of Leipzig and is set to reclaim his rightful place in the middle, where Rits could also return.
The hosts remain fortunate on the injury front, and Clement will be working with a full-strength squad for this pivotal contest, with the only real dilemma coming in the final third.
Kamal Sowah's re-introduction could see Charles De Ketelaere pushed into a central role, but Bas Dost will not want to drop out after netting his side's consolation in the defeat to Mechelen.
As for Leipzig, the hero of the hour against PSG - Dominik Szoboszlai - was forced off against Hoffenheim with an ankle issue, and Tyler Adams is out of this game through suspension.
Marsch has also been dealt another major blow with Dani Olmo, who is facing the prospect of no football until 2022 due to a torn muscle, and he is joined on the sidelines by Yussuf Poulsen, Mohamed Simakan, Marcel Halstenberg, Amadou Haidara and Konrad Laimer.
Emil Forsberg should make an immediate return to the attack with Szoboszlai out, while 18-year-old Ilaix Moriba can expect to start in midfield amid his side's injury woes.
Club Brugge possible starting lineup:
Mignolet; Mata, Hendry, Nsoki, Sobol; Balanta, Rits, Vanaken; Lang, Dost, De Ketelaere
RB Leipzig possible starting lineup:
Gulacsi; Klostermann, Orban, Gvardiol; Mukiele, Kampl, Moriba, Angelino; Nkunku, Forsberg; Silva
We say: Club Brugge 2-1 RB Leipzig
A Leipzig side low on numbers and confidence can still pose a major threat to this Brugge backline, especially with Nkunku simply unplayable in the Champions League this term.
The visitors' poor fortunes on the road have to end at some point, and even though Clement's side are going through a bit of a sticky patch themselves, an injury-hit Leipzig will likely fall short once again.
Top tip
Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Club Brugge win with a probability of 48.84%. A draw had a probability of 26.6% and a win for RB Leipzig had a probability of 24.54%.
The most likely scoreline for a Club Brugge win was 1-0 with a probability of 13.25%. The next most likely scorelines for that outcome were 2-0 (9.6%) and 2-1 (9.05%). The likeliest drawn scoreline was 1-1 (12.49%), while for a RB Leipzig win it was 0-1 (8.63%). The actual scoreline of 0-5 was predicted with a 0.1% likelihood.