Roma vs. Spezia (Saturday, 2.00pm)
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Reeling Roma and Serie A rookies Spezia reprise their dramatic midweek meeting this Saturday, as the Ligurian surprise package aim for unprecedented back-to-back wins at Stadio Olimpico.
A classic cup upset saw Vincenzo Italiano's inspired team knock out the nine-man Giallorossi on Tuesday and they now return to the scene of one of the great results in their history.
We say: Roma 2-1 Spezia
Being stung twice in succession has glaringly highlighted Roma's defensive flaws - an issue which has dogged Paulo Fonseca since taking charge.
However, his talented side can bounce back - motivated by their embarrassment - and edge past a spirited Spezia outfit on Saturday.
Our tipster partners are predicting a home win.
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AC Milan vs. Atalanta (Saturday, 5.00pm)
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League leaders AC Milan await the visit of near neighbours Atalanta BC on Saturday, with the opportunity arising for the Rossoneri to declare themselves 'winter champions' at Serie A's halfway stage.
This tantalising Lombardy derby pits Stefano Pioli's record-breaking outfit against an away side whose sparkling form has tailed off in the past week - with just two points and one goal from a pair of league fixtures.
We say: AC Milan 2-2 Atalanta BC
Both of these enterprising sides generally score for fun and should serve up a delight for neutrals and fans alike, as Atalanta are willing to go toe-to-toe with their bigger and bolder Lombardy neighbours.
A plethora of attacking talent at both coaches' disposal must surely create a fitting spectacle to draw the first half of the season to a belated close.
Our tipster partners are predicting a double chance bet on a home win or an away win.
> Click here to read our full preview for this match
Udinese vs. Inter Milan (Saturday, 5.00pm)
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Title-chasing Inter Milan travel to meet Udinese on Saturday in buoyant mood, as they continue their pursuit of a longed-for first Scudetto in a decade.
Decisive victory in the Derby d'Italia last week saw Inter claim a clear advantage over Juventus and stay in touch with league leaders Milan, while their Friulian hosts remain mired in trouble despite a hard-earned point in midweek.
We say: Udinese 1-3 Inter Milan
This is not the time or place for Udinese to break their barren run in Serie A, as Inter have the bit between their teeth at the moment and will prove hard to resist on Saturday.
Conte's men can utilise their ruthless streak to see off a second Bianconeri outfit in as many weeks - keeping closely on the coat-tails of upcoming Coppa Italia opponents Milan.
Our tipster partners are predicting a double chance bet on a home win or an away win.
> Click here to read our full preview for this match
Fiorentina vs. Crotone (Saturday, 7.45pm)
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Following two very different outcomes last week, shell-shocked Fiorentina welcome fellow strugglers Crotone to Stadio Artemio Franchi on Saturday evening.
La Viola's six-goal thrashing by Napoli was in stark contrast to an unexpected 4-1 win for Serie A's bottom side last weekend and the clubs are now separated by just six points.
We say: Fiorentina 1-0 Crotone
Under pragmatic Prandelli, Fiorentina can come back from their freak defeat to Napoli with a defensive display more in keeping with the past few weeks.
Therefore, the Viola's superior home record - allied to Crotone's miserable return when on their travels - should inspire enough confidence to see them seal maximum points in Florence.
Our tipster partners are predicting a double chance bet on a home win or an away win.