Liverpool boss Jurgen Klopp should not shy away from making several alterations for Sunday's Premier League battle with Fulham at Craven Cottage.
The Reds head to London on the back of a 3-1 aggregate loss to Atalanta BC in the Europa League quarter-finals, despite emerging victorious by a 1-0 scoreline in the second leg in Bergamo.
All of Ben Doak (knee), Conor Bradley (ankle), Joel Matip (knee) and Thiago Alcantara (muscle) were absent for that clash and remain out of contention, while a fitness-related question mark is hanging over Stefan Bajcetic's head.
Nevertheless, chopping and changing should be the order of the day for Klopp, who admitted that Trent Alexander-Arnold was running on empty in the second half of Thursday's game and should therefore swap the Englishman out for Joe Gomez.
Jarell Quansah is also in line for a defensive recall over Ibrahima Konate, but rearguard mainstays Andrew Robertson, Alisson Becker and Virgil van Dijk ought to reprise their roles here.
Alexis Mac Allister was another player whose energy stores were completely depleted in midweek, so Wataru Endo will likely return to the number six position, potentially with Dominik Szoboszlai and Harvey Elliott - replacing Curtis Jones - either side of him.
Mohamed Salah followed up his early penalty with a glaring miss on Thursday evening, but Klopp has insisted that he has no concerns about the form of the Egyptian, who will likely start again after being substituted midway through the second half in Bergamo.
Cody Gakpo and Luis Diaz are at risk of the axe, though, as Darwin Nunez - who boasts the worst big-chance conversion percentage in Europe's top five leagues - and Diogo Jota, the only Liverpool attacker to have out-performed his Expected Goals (xG) this season, push for recalls.
Liverpool possible starting lineup:
Alisson; Gomez, Quansah, Van Dijk, Robertson; Elliott, Endo, Szoboszlai; Salah, Nunez, Jota