Newcastle will head into Wednesday's fixture as favourites considering their recent form, position in the table and record on home soil, while Everton's poor away form also bodes well for the hosts.
The Toffees have scored in 20 of their last 21 encounters with Newcastle, but they may struggle to breach a resilient Magpies backline on this occasion, with Howe's side also possessing enough quality to come away with all three points despite the absence of Isak and Saint-Maximin.
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Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Newcastle United win with a probability of 61.75%. A draw had a probability of 21.3% and a win for Everton had a probability of 16.94%.
The most likely scoreline for a Newcastle United win was 1-0 with a probability of 11.05%. The next most likely scorelines for that outcome were 2-0 (10.83%) and 2-1 (9.92%). The likeliest drawn scoreline was 1-1 (10.12%), while for a Everton win it was 0-1 (5.17%). The actual scoreline of 1-0 was predicted with an 11.1% likelihood. Our data analysis correctly predicted a 1-0 win for Newcastle United in this match and our team at Sports Mole correctly predicted the win for Newcastle United.