Delon Armitage is expected to replace Mark Cueto on the wing in England's final Pool B match against Scotland on Saturday.
Armitage impressed against Argentina and Georgia, but Cueto opened his World Cup account with a hat-trick against Romania in their previous match.
Matt Stevens is likely to feature ahead of Alex Corbisiero at loose-head prop, while Courtney Lawes could return after serving a two-match ban.
Meanwhile, Scotland forwards Kelly Brown and Jim Hamilton are both injury doubts.