Northern Premier League side Blyth Spartans will travel to League Two Hartlepool United in the second round of the FA Cup.
Warrington Town, who are the lowest-ranked side left in the competition, have been rewarded with a visit to Gateshead following their victory over Exeter City.
Eastleigh of the Conference travel to either Dagenham & Redbridge or Southport, while Barnsley will play host to Chester.
Should 2008 winners Portsmouth beat Aldershot Town in their first-round replay, then they will welcome either Northampton Town or Rochdale to Fratton Park.
FA Cup second-round draw in full:
Oxford United vs. Tranmere Rovers
Bury vs. Luton Town
Wrexham vs. Stevenage/ Maidstone United
Scunthorpe United vs. Worcester City
Colchester United vs. Peterborough United
Wycombe Wanderers vs. York City/ AFC Wimbledon
Notts County or Accrington Stanley vs. Yeovil Town
Hartlepool United vs. Blyth Spartans
MK Dons vs. Chesterfield
Dagenham & Redbridge/ Southport vs. Eastleigh
Gateshead vs. Warrington Town
Oldham Athletic vs. Weston-Super-Mare/ Doncaster Rovers
Havant & Waterlooville/ Preston North End vs. Walsall/ Shrewsbury Town
Barnsley vs. Chester
Bradford City vs. Dartford
Crewe Alexandra/ Sheffield United vs. Plymouth Argyle
Cheltenham Town vs. Dover Athletic
Cambridge United vs. Mansfield Town/ Concord Rangers
Bristol City vs. Basingstoke/ AFC Telford
Portsmouth/ Aldershot Town vs. Northampton Town/ Rochdale
Ties will be played on December 5, 6, 7 and 8.
