Brentford vs. Spurs (Sunday, 2.00pm)
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Overshadowed by the departure of their vice-captain and leading goalscorer, Tottenham Hotspur kick off the new Premier League season with a visit to Brentford on Sunday.
As the start of a post-Harry Kane era looms large for the Lilywhites, a Spurs side under new management will take on London rivals missing their own star striker until the start of next year.
We say: Brentford 2-2 Tottenham Hotspur
A fascinating match-up between two front-foot coaches awaits on the Premier League's opening weekend, as Frank's philosophy comes up against 'Angeball' - albeit in the latter's infancy at Spurs. Despite either team missing an England striker compared to last season's lineups, goals should be on the cards at Brentford Community Stadium, where the points could ultimately be shared.
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> How Tottenham could line up against Brentford
> Tottenham injury, suspension list vs. Brentford
Chelsea vs. Liverpool (Sunday, 4.30pm)
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Mauricio Pochettino begins his reign as Chelsea head coach with a blockbuster Premier League opener against Jurgen Klopp's Liverpool at Stamford Bridge on Sunday afternoon.
The two English giants will endeavour to put aside their underwhelming top-flight efforts from last season and mount a stronger challenge for at least a top-four finish this time around.
We say: Chelsea 2-2 Liverpool
Both Chelsea and Liverpool have cancelled each other out in low-scoring affairs in recent years, and few would be surprised to see the spoils shared once again at Stamford Bridge on Sunday.
Nevertheless, an entertaining contest should be in store and there could be a greater level of goalmouth action this time around as the defences of both sides have been far from watertight in pre-season.
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> How Liverpool could line up against Chelsea
> How Chelsea could line up against Liverpool