The Swiss centre-back signed for the Whites from Arsenal in 2010 and has since gone on to make 68 appearances.
However, the West Londoners have now sanctioned his sale to their La Liga counterparts for an undisclosed fee.
The 28-year-old featured on 15 occasions for the Whites this season.
Restore Data
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Liverpool | 23 | 17 | 5 | 1 | 56 | 21 | 35 | 56 |
| 2 | Arsenal | 24 | 14 | 8 | 2 | 49 | 22 | 27 | 50 |
| 3 | Nottingham ForestNott'm Forest | 24 | 14 | 5 | 5 | 40 | 27 | 13 | 47 |
| 4 | Chelsea | 24 | 12 | 7 | 5 | 47 | 31 | 16 | 43 |
| 5 | Manchester CityMan City | 24 | 12 | 5 | 7 | 48 | 35 | 13 | 41 |
| 6 | Newcastle UnitedNewcastle | 24 | 12 | 5 | 7 | 42 | 29 | 13 | 41 |
| 7 | Bournemouth | 24 | 11 | 7 | 6 | 41 | 28 | 13 | 40 |
| 8 | Aston Villa | 24 | 10 | 7 | 7 | 34 | 37 | -3 | 37 |
| 9 | Fulham | 24 | 9 | 9 | 6 | 36 | 32 | 4 | 36 |
| 10 | Brighton & Hove AlbionBrighton | 24 | 8 | 10 | 6 | 35 | 38 | -3 | 34 |
| 11 | Brentford | 24 | 9 | 4 | 11 | 42 | 42 | 0 | 31 |
| 12 | Crystal Palace | 24 | 7 | 9 | 8 | 28 | 30 | -2 | 30 |
| 13 | Manchester UnitedMan Utd | 24 | 8 | 5 | 11 | 28 | 34 | -6 | 29 |
| 14 | Tottenham HotspurSpurs | 24 | 8 | 3 | 13 | 48 | 37 | 11 | 27 |
| 15 | West Ham UnitedWest Ham | 24 | 7 | 6 | 11 | 29 | 46 | -17 | 27 |
| 16 | Everton | 23 | 6 | 8 | 9 | 23 | 28 | -5 | 26 |
| 17 | Wolverhampton WanderersWolves | 24 | 5 | 4 | 15 | 34 | 52 | -18 | 19 |
| 18 | Leicester CityLeicester | 24 | 4 | 5 | 15 | 25 | 53 | -28 | 17 |
| 19 | Ipswich TownIpswich | 24 | 3 | 7 | 14 | 22 | 49 | -27 | 16 |
| 20 | Southampton | 24 | 2 | 3 | 19 | 18 | 54 | -36 | 9 |
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