Arsenal vs. Luton (Wednesday, 7.30pm)
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Twenty-four hours at the top of the Premier League table will be Arsenal's prize if they can return to victorious ways at home to Luton Town on Wednesday evening.
Mikel Arteta's gritty men snatched a praiseworthy point away from Manchester City at the weekend, whereas the Hatters failed to cling onto a 1-0 lead versus Tottenham Hotspur, going down 2-1 in North London.
We say: Arsenal 3-0 Luton Town
While Luton may have gleaned zero points from their trip to Tottenham, their grit and determination was made all the more impressive due to their eye-watering injury list, which is showing no signs of letting up before another taxing North London trip.
Faced with the best attack and defence in the Premier League, though, the Hatters' prolific run in front of goal should finally come to an end, as the Gunners run riot against their ravaged visitors to ascend to first place.
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> How Arsenal could line up against Luton Town
> Saka, Timber - Arsenal injury latest ahead of Luton clash
Brentford vs. Brighton (Wednesday, 7.30pm)
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The Bees host the Seagulls in Wednesday's Premier League avian battle, as Brentford welcome Brighton & Hove Albion to the Gtech Community Stadium.
Thomas Frank's men salvaged a point off of Manchester United in a chaotic injury-time period on Saturday, before Roberto De Zerbi's side fell to a 2-1 loss to new leaders Liverpool.
We say: Brentford 1-1 Brighton & Hove Albion
Both Brentford and Brighton did themselves proud against two titans of the English game over the Easter weekend, although Welbeck's opener is the only away goal that the Seagulls have managed in their last four road contests.
However, faced with a Bees side - albeit an improving one - that cannot bolt the back door shut at their Gtech base, a solitary strike may be enough for De Zerbi's troops to depart with a point as the hosts' winless run continues.
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Man City vs. Aston Villa (Wednesday, 8.15pm)
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Third hosts fourth in Wednesday's Premier League showdown at the Etihad Stadium, as Manchester City pit their wits against Aston Villa.
The reigning champions settled for a point in a goalless draw with title rivals Arsenal at the weekend, while Unai Emery's charges were convincing 2-0 winners over Wolverhampton Wanderers.
We say: Manchester City 2-0 Aston Villa
With Emery's former employers Arsenal frustrating Man City to excellent effect with their defensive stance, it will be interesting to see whether the Villa boss opts for such a conservative setup or persists with his risky high line, which Guardiola's men can certainly exploit.
The Lions have proven highly resilient on the road either way, but with Watkins emerging as a serious doubt and their hosts able to switch up their attacking resources, we can only envisage Man City making it 14 home wins on the bounce against the visitors to get their title defence back on track.
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