Cambridge vs. Exeter (Saturday, 12.30pm)
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As the threat of relegation looms, Cambridge United are set to host Exeter City at Cledara Abbey Stadium this Saturday in League One.
The U's are alone at the bottom of the table and will be desperate to avoid falling further from safety this weekend, while the Grecians have lost four on the bounce and may be vulnerable.
We say: Cambridge United 2-1 Exeter City
Cambridge may be at the bottom of the table, but they will sense the opportunity to win this weekend given their opponents are in exceptionally poor form.
That being said, Exeter are likely to score considering the U's have not kept a clean sheet since November, though Monk's side should still take all three points on Saturday.
> League One preview: Cambridge vs Exeter
Northampton vs. Wrexham (Saturday, 12.30pm)
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Aiming to ramp up the pressure on the top two in the League One table, Wrexham will travel to Sixfields Stadium to take on Northampton Town on Saturday.
The visitors moved within four points of second spot with a return to winning ways last time out, while their hosts have climbed to 17th spot with important back-to-back victories.
We say: Northampton Town 2-2 Wrexham
With renewed confidence having ended a tough run with a pair of impressive victories, Northampton Town should certainly cause problems for a Wrexham side who are weaker on the road than they are on home turf.
That new momentum could see Nolan's men take another creditable point in what may be an eventful contest at Sixfields.
> League One preview: Northampton vs Wrexham
Barnsley vs. Huddersfield (Saturday, 3.00pm)
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Barnsley will welcome Huddersfield Town to Oakwell on Saturday for a Yorkshire Derby of major importance in the fight for top-six spots in the League One table.
Both in the midst of winless runs, the hosts now sit 10th while their visitors have dropped to sixth spot and only lead the chasing pack by two points.
We say: Barnsley 1-2 Huddersfield Town
Saturday's game promises to be a crucial one between two sides desperate to get promotion bids back on track at Oakwell.
It is arguably the visitors who have the stronger quality to overcome their rut, while Barnsley are yet to show their dominance at Oakwell this term, and we back Michael Duff to prevail over his old side as a result.
> League One preview: Barnsley vs Huddersfield
Birmingham vs. Charlton (Saturday, 3.00pm)
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Looking to continue their canter towards the Championship, league leaders Birmingham City will host Charlton Athletic at St Andrew's @ Knighthead Park on Saturday afternoon in League One.
Blues enjoyed a routine success over bottom side Cambridge United earlier in the week, whilst the Addicks' good form continued against Peterborough United.
We say: Birmingham City 1-0 Charlton Athletic
Following the ease of victory against Cambridge earlier in the week, Birmingham should expect a harder test from in-form Charlton this weekend.
The Addicks have a better chance than many of breaking Blues' League One invincibility at St Andrew's, although we feel that the visitors will fall narrowly short in the Second City.
> League One preview: Birmingham vs Charlton
Blackpool vs. Mansfield (Saturday, 3.00pm)
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Dreaming of joining the race for promotion in League One, Blackpool are set to host struggling Mansfield Town at Bloomfield Road on Saturday.
The Seasiders could extend their unbeaten streak to 10 matches this weekend, while the Stags have lost seven on the bounce and will be desperate to avoid making it eight.
We say: Blackpool 1-1 Mansfield Town
Blackpool seem to be simultaneously unbeatable and incapable of earning a win, so expect another stalemate this weekend.
To add to this, Mansfield will be desperate to gain some stability after a horrendous run of results, and a point on the road to the Seasiders would be a good start.
> League One preview: Blackpool vs Mansfield
Bristol Rovers vs. Burton Albion (Saturday, 3.00pm)
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In a potential relegation six-pointer, Bristol Rovers will welcome Burton Albion to Memorial Stadium on Saturday in League One.
The Gas will be looking to make it three games unbeaten this weekend, while the Brewers are in surprisingly strong form for a side in the relegation zone.
We say: Bristol Rovers 1-2 Burton Albion
Rovers may have the advantage in league position, but the momentum is with Burton ahead of this clash.
The fact that the Brewers have been so strong both in 2025 and on the road in general for the past few months is difficult to ignore, and the visitors will likely take another step towards survival with three points on Saturday.
> League One preview: Bristol Rovers vs Burton Albion
Crawley vs. Wycombe (Saturday, 3.00pm)
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High-flying Wycombe Wanderers travel to Crawley Town in League One this weekend, looking to continue their push for promotion to the Championship.
The Chairboys are currently second in the League One table, seven points behind the league leaders, Birmingham City.
We say: Crawley Town 0-2 Wycombe Wanderers
Wycombe have been excellent this season, and we cannot look past them in this weekend's match.
Crawley are down at the wrong end of the table, and despite them picking up a win on Tuesday, we expect the visitors to take the three points this weekend.
> League One preview: Crawley vs Wycombe
Leyton Orient vs. Lincoln (Saturday, 3.00pm)
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Two playoff hopefuls square off in League One this weekend, as Leyton Orient host Lincoln City at the Gaughan Group Stadium.
Orient come into the weekend's action sitting just outside the playoff zone in seventh, while Lincoln are 12th in the table and nine points off the playoffs.
We say: Leyton Orient 2-0 Lincoln City
Orient look the real deal this year, and we think that they are in a good position to earn promotion to the Championship, despite sitting just outside the playoff zone at present.
A win would potentially lift them into the playoff zone, and we think that they will keep another clean sheet here in a comfortable home win.
> League One preview: Leyton Orient vs Lincoln
Reading vs. Rotherham (Saturday, 3.00pm)
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Both aiming to get back to winning ways after midweek draws, Reading and Rotherham United will do battle at the Select Car Leasing Stadium on Saturday.
The hosts currently sit ninth in the League One table and three points outside of the playoff spots, while their visitors have dropped back down to 14th spot in the midst of a three-match winless run.
We say: Reading 2-1 Rotherham United
With the visitors off the pace again in their League One campaign, despite the quality in their squad, we back Reading to reignite their playoff push with a narrow home victory on Saturday.
> League One preview: Reading vs Rotherham
Shrewsbury vs. Bolton (Saturday, 3.00pm)
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Shrewsbury Town host Bolton Wanderers this weekend, looking to move closer to safety in the League One table.
The Shrews are currently occupying a place in the relegation zone, as they sit 21st in the table, while their opponents are eighth, just two points off the playoff positions.
We say: Shrewsbury Town 1-1 Bolton Wanderers
Had this fixture been played earlier in the season, we would have picked Bolton to win the match, just as they did in the League Cup back in August.
However, Shrewsbury have hit a good run of late, and we think that they will grab a share of the spoils this weekend in an entertaining draw.
> League One preview: Shrewsbury vs Bolton
Stevenage vs. Peterborough (Saturday, 3.00pm)
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With their League One status at risk, Peterborough United will travel to take on Stevenage at the Lamex Stadium on Saturday.
The Boro come into the clash looking to end a three-game losing streak and may be low on confidence, while the Posh are just three points above the drop zone and will be desperate to avoid defeat at the very least.
We say: Stevenage 1-1 Peterborough United
Stevenage have been in poor form in recent weeks, but Peterborough have a shocking record away from home this season.
The Boro are likely to score given the Posh have conceded the most goals in the league, but the visitors can also be expected to find the back of the net in a score draw.
> League One preview: Stevenage vs Peterborough
Wigan vs. Stockport (Saturday, 3.00pm)
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Stockport County travel to Wigan Athletic this weekend, looking to maintain their bid for promotion to the Championship next season.
Heading into the weekend's action, the Hatters are currently fourth in the standings in League One on 54 points, while Wigan are 20 points behind the visitors in 16th position.
We say: Wigan Athletic 1-2 Stockport County
Stockport need to keep winning to continue their promotion push, and we think they will edge a tight encounter against Wigan this weekend.
The Latics have not got the best record at home this season and the Hatters should look to profit from that in this clash.